InterPro in 2017––beyond protein family and domain annotations

Author(s)Finn, Robert D.
Author(s)Attwood, Teresa K.
Author(s)Babbitt, Patricia C.
Author(s)Bateman, Alex
Author(s)Bork, Peer
Author(s)Bridge, Alan J.
Author(s)Chang, Hsin-Yu
Author(s)Doszt´anyi, Zsuzsanna
Author(s)El-Gebali, Sara
Author(s)Fraser, Matthew
Author(s)Gough, Julian
Author(s)Haft, David
Author(s)Holliday, Gemma L.
Author(s)Huang, Hongzhan
Author(s)Huang, Xiaosong
Author(s)Letunic, Ivica
Author(s)Lopez, Rodrigo
Author(s)Lu, Shennan
Author(s)Marchler-Bauer, Aron
Author(s)Mi, Huaiyu
Author(s)Mistry, Jaina
Author(s)Natale, Darren A.
Author(s)Necci, Marco
Author(s)Nuka, Gift
Author(s)Orengo, Christine A.
Author(s)Park, Youngmi
Author(s)Pesseat, Sebastien
Author(s)Piovesan, Damiano
Author(s)Potter, Simon C.
Author(s)Rawlings, Neil D.
Author(s)Redaschi, Nicole
Author(s)Richardson, Lorna
Author(s)Rivoire, Catherine
Author(s)Sangrador-Vegas, Amaia
Author(s)Sigrist, Christian
Author(s)Sillitoe, Ian
Author(s)Smithers, Ben
Author(s)Squizzato, Silvano
Author(s)Sutton, Granger
Author(s)Thanki, Narmada
Author(s)Thomas, Paul D.
Author(s)Tosatto, Silvio C. E.
Author(s)Wu, Cathy H.
Author(s)Xenarios, Ioannis
Author(s)Yeh, Lai-Su
Author(s)Young, Siew-Yit
Author(s)Mitchell, Alex L.
Ordered AuthorRobert D. Finn, Teresa K. Attwood, Patricia C. Babbitt, Alex Bateman, Peer Bork, Alan J. Bridge, Hsin-Yu Chang, Zsuzsanna Doszt´anyi, Sara El-Gebali, Matthew Fraser, Julian Gough, David Haft, Gemma L. Holliday, Hongzhan Huang, Xiaosong Huang, Ivica Letunic, Rodrigo Lopez, Shennan Lu, Aron Marchler-Bauer, Huaiyu Mi, Jaina Mistry, Darren A Natale, Marco Necci, Gift Nuka, Christine A. Orengo, Youngmi Park, Sebastien Pesseat, Damiano Piovesan, Simon C. Potter, Neil D. Rawlings, Nicole Redaschi, Lorna Richardson, Catherine Rivoire, Amaia Sangrador-Vegas, Christian Sigrist, Ian Sillitoe, Ben Smithers, Silvano Squizzato, Granger Sutton, Narmada Thanki, Paul D Thomas, Silvio C. E. Tosatto, Cathy H.Wu, Ioannis Xenarios, Lai-Su Yeh, Siew-Yit Young and Alex L. Mitchell
UD AuthorWu, Cathy H.en_US
UD AuthorHuang, Hongzhan
Date Accessioned2017-05-15T14:12:15Z
Date Available2017-05-15T14:12:15Z
Copyright DateThe Author(s) 2016en_US
Publication Date2016-11-28
DescriptionPublisher's PDFen_US
AbstractInterPro (http://www.ebi.ac.uk/interpro/) is a freely available database used to classify protein sequences into families and to predict the presence of important domains and sites. InterProScan is the underlying software that allows both protein and nucleic acid sequences to be searched against Inter- Pro’s predictive models, which are provided by its member databases. Here, we report recent developments with InterPro and its associated software, including the addition of two new databases (SFLD and CDD), and the functionality to include residue-level annotation and prediction of intrinsic disorder. These developments enrich the annotations provided by InterPro, increase the overall number of residues annotated and allow more specific functional inferences.en_US
DepartmentUniversity of Delaware. Center for Bioinformatics & Computational Biology.en_US
DepartmentUniversity of Delaware. Department of Computer and Information Sciences.
CitationRobert D. Finn, Teresa K. Attwood, Patricia C. Babbitt, Alex Bateman, Peer Bork, Alan J. Bridge, Hsin-Yu Chang, Zsuzsanna Dosztányi, Sara El-Gebali, Matthew Fraser, Julian Gough, David Haft, Gemma L. Holliday, Hongzhan Huang, Xiaosong Huang, Ivica Letunic, Rodrigo Lopez, Shennan Lu, Aron Marchler-Bauer, Huaiyu Mi, Jaina Mistry, Darren A. Natale, Marco Necci, Gift Nuka, Christine A. Orengo, Youngmi Park, Sebastien Pesseat, Damiano Piovesan, Simon C. Potter, Neil D. Rawlings, Nicole Redaschi, Lorna Richardson, Catherine Rivoire, Amaia Sangrador-Vegas, Christian Sigrist, Ian Sillitoe, Ben Smithers, Silvano Squizzato, Granger Sutton, Narmada Thanki, Paul D Thomas, Silvio C. E. Tosatto, Cathy H. Wu, Ioannis Xenarios, Lai-Su Yeh, Siew-Yit Young, Alex L. Mitchell; InterPro in 2017—beyond protein family and domain annotations. Nucleic Acids Res 2017; 45 (D1): D190-D199. doi: 10.1093/nar/gkw1107en_US
DOI10.1093/nar/gkw1107en_US
ISSN1362-4962en_US
URLhttp://udspace.udel.edu/handle/19716/21353
LanguageEnglishen_US
PublisherOxford University Pressen_US
dc.rightsCC-BY 4.0en_US
dc.sourceNucleic Acids Researchen_US
dc.source.urihttps://academic.oup.com/naren_US
TitleInterPro in 2017––beyond protein family and domain annotationsen_US
TypeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
InterPro in 2017—beyond protein family and domain annotations_1492792560T0699.pdf
Size:
2.38 MB
Format:
Adobe Portable Document Format
Description:
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
2.22 KB
Format:
Item-specific license agreed upon to submission
Description: